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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIAS1
All Species:
19.39
Human Site:
S450
Identified Species:
42.67
UniProt:
O75925
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75925
NP_057250.1
651
71836
S450
Q
V
A
S
H
H
Q
S
S
N
K
N
K
K
V
Chimpanzee
Pan troglodytes
XP_523109
766
83908
S565
Q
V
A
S
H
H
Q
S
S
N
K
N
K
K
V
Rhesus Macaque
Macaca mulatta
XP_001082800
642
70843
S442
V
A
S
H
H
Q
S
S
N
K
N
K
K
V
E
Dog
Lupus familis
XP_535524
651
71773
S450
Q
V
A
S
H
H
Q
S
S
N
K
N
K
K
V
Cat
Felis silvestris
Mouse
Mus musculus
O88907
651
71599
S450
Q
V
A
S
H
N
Q
S
S
N
K
N
K
K
V
Rat
Rattus norvegicus
O70260
628
68345
L428
P
G
Y
G
L
D
G
L
Q
Y
S
P
V
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516107
756
82793
S549
Q
V
S
S
H
Q
Q
S
S
N
K
N
K
K
V
Chicken
Gallus gallus
NP_001026627
564
62782
Q364
F
D
A
T
L
Y
I
Q
M
N
E
K
K
P
T
Frog
Xenopus laevis
NP_001079161
649
71676
H449
H
Q
V
P
S
N
H
H
S
S
N
K
N
K
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94361
793
89556
G543
C
S
S
T
N
G
N
G
L
A
N
E
A
A
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q680Q4
884
97015
I478
L
C
P
S
A
V
D
I
K
R
K
M
E
M
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.9
98.6
99.6
N.A.
98
58.6
N.A.
82.2
82.9
87
N.A.
N.A.
N.A.
N.A.
24
N.A.
Protein Similarity:
100
84.9
98.6
99.8
N.A.
98.7
72
N.A.
84.2
85
94.3
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
100
100
20
100
N.A.
93.3
0
N.A.
86.6
20
13.3
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
33.3
100
N.A.
100
6.6
N.A.
93.3
40
26.6
N.A.
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
46
0
10
0
0
0
0
10
0
0
10
10
0
% A
% Cys:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
10
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
10
10
10
0
19
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
10
0
10
10
10
0
0
0
0
0
0
0
% G
% His:
10
0
0
10
55
28
10
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
10
10
55
28
64
55
19
% K
% Leu:
10
0
0
0
19
0
0
10
10
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
10
0
10
0
% M
% Asn:
0
0
0
0
10
19
10
0
10
55
28
46
10
0
0
% N
% Pro:
10
0
10
10
0
0
0
0
0
0
0
10
0
10
0
% P
% Gln:
46
10
0
0
0
19
46
10
10
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% R
% Ser:
0
10
28
55
10
0
10
55
55
10
10
0
0
0
0
% S
% Thr:
0
0
0
19
0
0
0
0
0
0
0
0
0
0
10
% T
% Val:
10
46
10
0
0
10
0
0
0
0
0
0
10
10
46
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
10
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _